Postdoctoral fellow in multi-omics microbiome bioinformatics University of Copenhagen, Novo Nordisk Foundation Center for Basic Metabolic Research Denmark

Postdoctoral fellow in multi-omics microbiome bioinformatics


The Novo Nordisk Foundation Center for Basic Metabolic Research is seeking a candidate to fill a time-limited 2-year position, with possibilities of extension, to work on computational analysis of multi-omics data from the human gut microbiome. The position is in the Microbiome Systems Biology group led by Associate Professor Manimozhiyan Arumugam. The starting date is 1 August 2018 or as soon as possible thereafter.  
 
 
Background  
 
The Novo Nordisk Foundation Center for Basic Metabolic Research (CBMR) has been established at the Faculty of Health Sciences, University of Copenhagen to conduct basic research on metabolism (cbmr.ku.dk). The Center, which consists of six scientific sections and a number of international research satellites, was established through a DKK 885 million unrestricted grant from the Novo Nordisk Foundation. The available postdoctoral fellowship is in the Section of Metabolic Genetics, headed by Scientific Director Professor Torben Hansen.  
 
 
You can read more about the Novo Nordisk Foundation Center for Basic Metabolic Research on http://cbmr.ku.dk/
 
 
The human microbiota, the collection of trillions of microbes inhabiting the human body, has a strong influence on human health and diseases. The Arumugam group investigates the role of gut microbiota in several diseases – including type 2 diabetes, obesity, liver fibrosis, colorectal cancer and multiple sclerosis – using human cohorts and animal models. These studies involve integrated analysis of multi-omics data (including metagenomics, metatranscriptomics, host genetics, and host transcriptomics) and clinical/metabolic phenotypes to better understand the role of gut microbiota in diseases. The group has access to a high-performance computing cluster with more than 500 CPUs to support these and other computational projects.  
 
 
More information about the group can be found at:http://cbmr.ku.dk/research/section-for-metabolic-genetics/arumugam-group/, http://research.ku.dk/search/?pure=en/persons/441006
 
 
The advertised position relates to the GALAXY project funded by the European Union’s Horizon 2020 framework. GALAXY investigates the gut and liver axis in alcoholic liver fibrosis using host-microbial multi-omics consisting genetics, microRNAs, metabolomics, gut metagenomics (shotgun sequencing), gut metatranscriptomics. Successful candidate will be integrating this multi-omics data in collaboration with the workpackage leader European Molecular Biology Laboratory (EMBL) and other project partners in GALAXY.  
 
 
More information about GALAXY can be found at www.livergalaxy.eu
 
 
Job Description  

The position is a 2 year postdoctoral fellowship in computational biology under the supervision of Associate Professor Manimozhiyan Arumugam, where the candidate will be responsible for developing novel tools to analyze microbiome and multi-omics data in the context of alcoholic liver fibrosis, while also incorporating and improving existing state-of-the-art tools. He/she is expected to participate in and lead existing projects within GALAXY, and is highly encouraged to initiate new cutting-edge research projects. He/she is also expected to interact and collaborate with other medical researchers, biologists, and bioinformaticians in the Section, the Centre, and the GALAXY consortium, to enhance and ensure proper interpretation of experimental results.  
 
 
Qualification requirements  
 
In connection with the appointment to the post, special importance will be attached to the applicant having the professional and personal qualifications stated below: 
  • PhD in bioinformatics, or in computer science (informatics) with experience in bioinformatics research, or in biology with strong experience in software development  
  • Academic preparation as well as experience in machine learning and statistical analysis  
  • Experience in handling next-generation sequencing data  
  • Strong programming skills in C/C++, Java, Perl, or Python  
  • Experience in statistical computing environments such as R  
  • Experience in high performance computing environment using any flavour of UNIX  
  • An excellent research record exemplified by strong publications  
  • Strong communication skills in English, both spoken and written, are essential 
 
The following qualifications are highly preferred, but not required. Candidates who possess any of these qualifications are encouraged to highlight them in the application: 
  • Basic understanding of human disease biology and/or microbiology
  • Experience in analyzing metagenomic datasets from human gut microbiota
  • Experience in handling multi-omics data, including metabolomics and proteomics
  • Experience in distributed and cloud computing technologies
  • Familiarity with bioinformatics programming environments such as BioPerl/BioPython/BioRuby 

Terms of employment  

General reference is made to the ministerial order on the employment of scientific staff at Danish universities – http://www.ubst.dk. The gross basic salary range for Postdoctoral Fellows is approximately DKK 33,000-34,000 per month (level 6 to 8). A supplement may be negotiated in addition to the basic salary but this is dependent on the candidate’s experience and qualifications. An additional 17.1% monthly contribution to pension will be paid by the employer.  
 
 
For more information on working and living in Denmark: http://ism.ku.dk.
 
 
Questions  
 
For further information, please contact Associate Professor Manimozhiyan Arumugam at arumugam@sund.ku.dk.
 
 
Application  
 
The application - in English - must include: 
  • A letter of motivation  
  • Curriculum vitae  
  • Publications list  
  • At least two letters of references, maximum four  
  • Documentation of research and optionally teaching qualifications
 
Please apply by clicking “Apply Now” below or via this advertisement on http://employment.ku.dk/faculty/
 
 
The deadline for applications is 20 June 2018, 23:59 CET.

 
Any applications received after this time will not be considered. Receipts of the applications will be acknowledged within 24 hours, and the applicant will be kept continuously informed of the progress of the process.  
 
 
The further process  
 
Shortlist: After expiry of the application deadline, the superior with power to appoint selects a number of applicants for assessment on the advice of the Appointment Committee. All applicants are immediately notified whether their application has been passed for assessment. Applicants who were not passed for assessment should not expect further with regard to their application unless the shortlist is revised.
 
 
Assessment: The selected applications will be assessed according to the Ministry Order on the Appointment of Academic Staff at Universities 2012 and the University of Copenhagen’s guidelines 2013. The Assessment Committee makes a non-prioritized assessment of the academic qualifications and experience with respect to the above mentioned area of research, techniques, skills and other requirements listed in the advertisement.  
 
 
You can read about the recruitment process at http://employment.ku.dk/faculty/recruitment-process/
 
 
As an equal opportunities employer, the University welcomes applications from suitable qualified people, regardless of age, race, religion, gender or ethnic background.  


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