Assistant Researcher in Clinical Sciences
Lund University Faculty of Medicine
Sweden

Assistant Researcher in Clinical Sciences

Department of Clinical Sciences, Malmö

Lund University was founded in 1666 and is repeatedly ranked among the world’s top 100 universities. The University has 40 000 students and 7 600 staff based in Lund, Helsingborg and Malmö. We are united in our efforts to understand, explain and improve our world and the human condition.

The Faculty of Medicine is a part of Lund University, and is responsible for education and research within medicine and healthcare. Our academic programs are closely linked with the healthcare system and are firmly anchored in the faculty’s strong research tradition. Our research spans a broad field within experimental preclinical research, near-patient clinical research and health sciences research. The Faculty of Medicine, with its 1,800 employees and 2,700 students in Lund and Malmö, is a knowledge-intensive meeting place for students, teachers and researchers from all over the world.

The Department of Clinical Sciences, Malmö is one of the six departments at the Faculty of Medicine, Lund University. We have a strong focus on clinical and epidemiological research and also conduct an extensive preclinical laboratory research.

The Research Group

The position is placed at the Department of Clinical Sciences in Malmö, at the Diabetic Complications Research Unit and within the environment of the Lund University Diabetes Centre (LUDC; www.ludc.med.lu.se).

LUDC is one of the largest diabetes research centres in the world with approximately 300 investigators and staff members working towards improved diagnosis, prevention and treatment of diabetes and its complications. The centre combines expertise in genetics, epidemiology, statistics, bioinformatics, molecular and cellular biology, physiology and clinical diabetes and endocrinology to achieve these goals. LUDC has large unique biobanks and databases with genome-wide data linked to national registries providing information on disease aetiology, progression as well as outcome and treatment. The centre has in-house platforms for most molecular genetic methods and metabolomics. Omics-information combined with extensive phenotyping allows a systems medicine approach to dissect the complexity of diabetes. A central theme of the Centre is to develop precision medicine to improve health and the quality of life of diabetic patients.

The research will be carried out within the project “Novel molecular mechanisms underlying diabetic complications”. Cardiovascular and kidney complications are the major cause of morbidity and mortality in diabetic patients. Given the rising incidence of diabetes (expected to reach 700 million people worldwide by 2025), we find ourselves addressing an increasingly sick and underserved population owing to therapeutic limitations, with mortality rates exceeding those of most cancers. The overall purpose of the project is to identify targetable mechanisms and pathways underlying initiation and progression of diabetic complications.

This is a full time position and limited for two years. Start April 1 or according to agreement.


Work duties

The main duty is to conduct research. As Assistant Researcher you will be working together with other members of the Diabetic Complications Unit

( https://www.ludc.lu.se/research/diabetic-complications). Our group leads and participates in several large national and international consortia for the study of diabetes, diabetic complications and cardiovascular disease. The candidate will work at the interface of basic and translational research and he/she is expected to have excellent communication skills, a willingness to interact with other researchers and to contribute to the common goals of the unit and of the centre.

The work involves the use of a large repertoire of experimental tools and techniques well-established in our laboratory. Anticipated duties are indicated in, but not limited to the list below:

-Laboratory animal work including breeding, genotyping and phenotyping of various rodent models of disease, as well as functional in vivo studies/drug intervention studies. Longitudinal measurements of blood pressure (both tail cuff and telemetry) and of endothelial function, glucose and insulin tolerance tests, blood and urine collection and studies using metabolic cages.

-Handling of animal and human samples (biofluids, cells and biopsies), DNA, RNA or protein extraction for further analyses or preparation of samples for sectioning and histology or immunohistochemistry/immunofluorescence. Microscopy (i.e. fluorescence, confocal, EM) and stereological techniques for qualitative and quantitative image analyses and for live studies.

-Basic cell and molecular biology laboratory work, including western-blotting, ELISA, RT-PCR, gene editing, cloning, cell and organ culture techniques (i.e. proliferation, migration, apoptosis assays, differentiation of circulating progenitor cells).

-Participation in planning and study design together with the PI and team

-Presentation of research results at seminars, conferences and other relevant contexts (both orally and in written)

- Contribution to applying for research funding, to grant reporting and to writing ethical permits

-Administration connected to the work duties listed above (may include ordering or reagents, supplies, managing equipment and service agreements)

-Supervision of undergraduate and graduate students involved in the project

 

Qualifications

Required skills:

  • Appointment to this position requires that the applicant has a PhD within the subject of the position
  • Relevant research background and experience in the Cardiovascular, Renal or Diabetes fields
  • Relevant research background for the research and work duties in the project 
  • A strong publication record (at least one first author in a recognized international journal in the field)
  • Documented oral and written proficiency in English
  • Documented training in biostatistics and experience in e.g. power calculations and using software for basic statistical analyses  
  • Interest in learning new approaches and methods that may include the use of modern, advanced equipment Experience of working in an international environment
  • Excellent verbal and written communication skills


Preferred skills:

  • A completed first post-doctoral experience after obtaining a PhD
  • Experience from work with microarray and next generation sequencing data
  • Experience of work with biomarkers
  • Teaching experience


Assessment criteria and other qualification:

This is a career development position primarily focused on research. The position is intended as an initial career step, and the assessment of the applicants will primarily be based on their research qualifications and potential as researchers. Particular emphasis will be placed on research skills within the subject, a good ability to develop and conduct high quality research and good analytical skills and ability to understand and assimilate different research perspectives.

We will also pay attention to personal attributes, favouring individuals that are flexible, social and used to collaborative work, taking initiatives and working in a well-documented way. Consideration will also be given to how the applicant’s experience and skills complement and strengthen ongoing research within the unit, and how they stand to contribute to its future development.

For further information please contact: Maria.Gomez@med.lu.se

Lund University welcomes applicants with diverse backgrounds and experiences. We regard gender equality and diversity as a strength and an asset. We kindly decline all sales and marketing contacts.

 

Please include the following in your application:

A complete curriculum vitae, including: date of the thesis defense, title of the thesis, previous academic positions, academic title, current position and academic distinctions. A complete list of publications (numbered, in chronological order, name of applicant highlighted in bold, all authors included – do not use “et al”) A one page cover letter summarizing previous experience, research interests, and motivation for position Names and contact details for three references that are familiar with the applicant’s recent research and training, including the PhD supervisor.

 

Lund University welcomes applicants with diverse backgrounds and experiences. We regard gender equality and diversity as a strength and an asset. We kindly decline all sales and marketing contacts.

To apply, please click the button "Login and apply"

 

Type of employment Temporary position longer than 6 months
Contract type Full time
First day of employment According to agreement
Salary Monthly
Number of positions 1
Working hours 100
City Malmö
County Skåne län
Country Sweden
Reference number PA2020/737
Contact
Maria Gomez, professor, maria.gomez@med.lu.se
Claes Moreau, personalsamordnare, claes.moreau@med.lu.se
Union representative
OFR/ST:Fackförbundet ST:s kansli, 046-222 93 62
SACO:Saco-s-rådet vid Lunds universitet, 046-222 93 64
Published 17.Mar.2020
Last application date 06.Apr.2020 11:59 PM CET


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