Doctoral Position in Endometriosis and Ovarian Cancer
University of Gothenburg Institute of Clinical Sciences
Sweden

Doctoral student in Medical Science - Endometriosis and ovarian cancer

Ref PAR 2021/386

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Project title: Endometriosis induced ovarian cancer; how, why and who? A study on precancer events, prediction and assaydevelopment for early detection.

Job assignments

The PhD education in Medical Science comprises carrying out a scientific project and completing at least 30 credits of courses at third-cycle level. The doctoral student must also write a scientific compilation thesis or monograph corresponding to at least 120 credits. For more information about third-cycle studies at Sahlgrenska Academy, see https://www.gu.se/en/sahlgrenska-akademin/doctoral-studies

Project: Endometriosis is a benign gynecological disease that affects between 10 and 20 percent of women of childbearing age. Ovarian endometriosis, endometrioma, has been shown in epidemiological studies to give a higher risk of developing so-called endometriosis-associated ovarian cancer (EAOC) of the clear cell and endometrioid type later in life. Understanding of the mechanisms underlying the development of EAOC is limited, but the higher incidence of gynecological cancer suggests common basic pathophysiology and disease etiology.

The project aims to increase understanding of the emergence of EAOC and to investigate clinically relevant markers for the identification of premalignant and early stages of EAOC. The studies will mostly be conducted as laboratory studies, but also include bioinformatics work, statistical analyzes, writing scientific articles and presenting results at national and international conferences. Laboratory techniques that will be used in the project are cell culture (establishment of primary culture and organoids). Next generation sequencing (NGS) with highly sensitive sequencing method (SiMSen-Seq). Analysis of gene expression with PCR-based techniques and analysis of proteins with relevant methods.

Third-cycle studies are equivalent to four year full-time and lead to a Degree of Doctor. Those appointed to doctoral studentships shall primarily devote themselves to their studies. Those appointed to doctoral studentships may, however, work to a limited extent with educational tasks, research and administration (departmental duties). Before a PhD degree has been awarded, duties of this kind may not comprise more than 20 per cent of a full-time post.

Eligibility

To be eligible for third-cycle studies, the applicant must meet both the general and specific entry requirements.

A person meets the general entry requirements for third-cycle studies if he or she:
1. has been awarded a second-cycle qualification
2. has satisfied the requirements for courses comprising at least 240 credits of which at least 60 credits were awarded in the second-cycle, or
3. has acquired substantially equivalent knowledge in some other way in Sweden or abroad

A person meets the specific entry requirements for third-cycle studies in Medical Science if he or she has successfully completed the English B/6 course or is considered to have acquired equivalent knowledge through previous studies

Assessment

In selecting between applicants who meet the general and specific entry requirements, their ability to benefit from third-cycle studies shall be taken into account. The assessment shall attach particular importance to documented qualifications for:
- specific knowledge and skills within the subject area and related research fields
- experience of scientific theory and relevant research methodology
- scientific analysis and presentation verified through thesis, degree project, scientific journals or the like.

Documented experience and knowledge in NGS related technologies, especially in SimSenSeq, cell culture (establishment of primary culture and organoids), and bioinformatics will be meritorious.

Employment

After admission to third-cycle studies you will be appointed to doctoral studentship. Regulations for employment of doctoral students are given in SFS 1993:100. The initial appointment may apply for no longer than one year. An appointment may be renewed for no more than two years at a time. A person may be appointed to a doctoral studentship for a total of eight years. The total employment period may, however, not exceed the time corresponding to full-time third-cycle study for four years.

Location: Sahlgrenska Academy, Institute of Clinical Sciences, Department of Obstetrics and Gynecology. Extent: 100%. First day of employment: as agreed.

Salaries for doctoral students are regulated in a local agreement at the University.  

For further information regarding the position

For more information about the project please contact the principal supervisor, 
Karin Sundfeldt, Professor, Institute of Clinical Sciences,
e-mail: karin.sundfeldt@gu.se 

Unions

Union representatives at the University of Gothenburg:
https://www.gu.se/en/about-the-university/work-at-the-university-of-gothenburg/how-to-apply

Information for International Applicants

Choosing a career in a foreign country is a big step. Thus, to give you a general idea of what we and Gothenburg have to offer in terms of benefits and life in general for you and your family/spouse/partner please visit:

https://www.gu.se/en/about-the-university/welcome-services

https://www.movetogothenburg.com/

How to apply

In order to apply for a position at the University of Gothenburg, you have to register an account in our online recruitment system. It is the responsibility of the applicant to ensure that the application is complete in accordance with the instructions in the job advertisement, and that it is submitted before the deadline.

You must include the following, in pdf format

  • Personal letter
  • CV
  • Diploma and transcripts showing that you meet with the general entry requirement
  • Proof of completion of  English 6 course or the acquired equivalent knowledge through previous studies

If your degree is from a university outside of Sweden, make sure that you attach a diploma and full transcripts that makes assessing your degree easier.  

If your degree has not been verified by a Swedish authority you need to provide contact details to the issuing university, registrar or similar, that can verify the degree at our request.

For information on what you need to submit in order to fulfill the English language requirement see https://www.universityadmissions.se/en/entry-requirements/english-language-requirements/

Closing date: 2021-05-25

The University of Gothenburg promotes equal opportunities, equality and diversity.

Applications will be destroyed or returned (upon request) two years after the decision of employment has become final. Applications from the employed and from those who appeal the decision will not be returned.

In connection to this recruitment, we have already decided which recruitment channels we should use. We therefore decline further contact with vendors, recruitment and staffing companies.

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