Doctoral Position in Medical Science
University of Gothenburg
Sweden

Doctoral student in Medical Science - Clinical Chemistry

Ref PAR 2021/952

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The University of Gothenburg tackles society’s challenges with diverse knowledge. 53 500 students and 6 500 employees make the university a large and inspiring place to work and study. Strong research and attractive study programmes attract scientists and students from around the world. With new knowledge and new perspectives, the University contributes to a better future.

Project title: Comparisons between new and established methods for analysis of treatment response in acute leukemia

Job assignments

The PhD education in Medical Science comprises carrying out a scientific project and completing at least 30 credits of courses at third-cycle level. The doctoral student must also write a scientific compilation thesis or monograph corresponding to at least 120 credits. For more information about third-cycle studies at Sahlgrenska Academy, see https://www.gu.se/en/sahlgrenska-akademin/doctoral-studies

Project: Acute leukemias are aggressive forms of cancer that affect blood-forming cells in the bone marrow. One reason for recurrence of acute leukemias, relapse, is that small amounts of leukemia cells have survived the treatment and remain in the bone marrow, so-called measurable (formerly minimal) residual disease (MRD). These remaining leukemia cells can cause recurrence of the disease, and the risk of recurrence is higher in the presence of MRD. In order to improve the prognosis for patients with acute leukemia, it is therefore very important to succeed in identifying the patients who carry the remaining leukemia cells. Several different methods are set up for the detection and quantification of MRD and which of the methods used depends on the type of leukemia the patient has. None of the methods is optimal, several need to be further evaluated, and in some patients none of the methods can be used. The overall purpose of this doctoral project is to improve the diagnosis of leukemia by evaluating existing methods and developing new methods for the detection of residual leukemia cells. The project includes performing various MRD analyses, primarily with targeted deep sequencing, extracting clinical data from databases and patient records, and statistical analyses regarding the performance of MRD analysis methods. 

The candidate should have good knowledge of hematology and clinical laboratory analysis methods as well as practical experience of MRD analyses in acute leukemias. To be able to obtain clinical and laboratory data, the candidate needs to be fluent in spoken and written Swedish, including a good medical vocabulary. Good ability to write scientific texts in English is desirable.

Third-cycle studies are equivalent to four year full-time and lead to a Degree of Doctor. Those appointed to doctoral studentships shall primarily devote themselves to their studies. Those appointed to doctoral studentships may, however, work to a limited extent with educational tasks, research and administration (departmental duties). Before a PhD degree has been awarded, duties of this kind may not comprise more than 20 per cent of a full-time post.

Eligibility

To be eligible for third-cycle studies, the applicant must meet both the general and specific entry requirements.

A person meets the general entry requirements for third-cycle studies if he or she:
1. has been awarded a second-cycle qualification
2. has satisfied the requirements for courses comprising at least 240 credits of which at least 60 credits were awarded in the second-cycle, or
3. has acquired substantially equivalent knowledge in some other way in Sweden or abroad

A person meets the specific entry requirements for third-cycle studies in Medical Science if he or she has successfully completed the English B/6 course or is considered to have acquired equivalent knowledge through previous studies

Assessment

In selecting between applicants who meet the general and specific entry requirements, their ability to benefit from third-cycle studies shall be taken into account. The assessment shall attach particular importance to documented qualifications for:
- specific knowledge and skills within the subject area and related research fields
- experience of scientific theory and relevant research methodology
- scientific analysis and presentation verified through thesis, degree project, scientific journals or the like.

Employment

After admission to third-cycle studies you will be appointed to doctoral studentship. Regulations for employment of doctoral students are given in SFS 1993:100. The initial appointment may apply for no longer than one year. An appointment may be renewed for no more than two years at a time. A person may be appointed to a doctoral studentship for a total of eight years. The total employment period may, however, not exceed the time corresponding to full-time third-cycle study for four years.

Location: Sahlgrenska Academy, Institute of Biomedicine, Department of Laboratory Medicine.
Extent: 100%. First day of employment: as agreed.

Salaries for doctoral students are regulated in a local agreement at the University. 

For further information regarding the position

For more information about the project please contact the principal supervisor, 
Linda Fogelstrand, Associate Professor, Institute of Biomedicine, e-mail:linda.fogelstrand@clinchem.gu.se 

Unions

Union representatives at the University of Gothenburg:
https://www.gu.se/en/about-the-university/work-at-the-university-of-gothenburg/how-to-apply

Information for International Applicants

Choosing a career in a foreign country is a big step. Thus, to give you a general idea of what we and Gothenburg have to offer in terms of benefits and life in general for you and your family/spouse/partner please visit:

https://www.gu.se/en/about-the-university/welcome-services

https://www.movetogothenburg.com/

How to apply

In order to apply for a position at the University of Gothenburg, you have to register an account in our online recruitment system. It is the responsibility of the applicant to ensure that the application is complete in accordance with the instructions in the job advertisement, and that it is submitted before the deadline.

You must include the following, in pdf format

  • Personal letter
  • CV
  • Diploma and transcripts showing that you meet with the general entry requirement
  • Proof of completion of  English 6 course or the acquired equivalent knowledge through previous studies

If your degree is from a university outside of Sweden, make sure that you attach a diploma and full transcripts that makes assessing your degree easier.  

If your degree has not been verified by a Swedish authority you need to provide contact details to the issuing university, registrar or similar, that can verify the degree at our request.

For information on what you need to submit in order to fulfill the English language requirement see https://www.universityadmissions.se/en/entry-requirements/english-language-requirements/

Closing date: 2021-07-26

The University of Gothenburg promotes equal opportunities, equality and diversity.

Applications will be destroyed or returned (upon request) two years after the decision of employment has become final. Applications from the employed and from those who appeal the decision will not be returned.

In connection to this recruitment, we have already decided which recruitment channels we should use. We therefore decline further contact with vendors, recruitment and staffing companies.

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