PhD Position in Integrative Physiology
Karolinska Institute Department of Physiology and Pharmacology

Doctoral (PhD) student position in Integrative Physiology

Do you want to contribute to better health for all?

To be a doctoral student means to devote oneself to a research project under supervision of experienced researchers and following an individual study plan. For a doctoral degree, the equivalent of four years of full-time doctoral education is required.

The research group

The Integrative Physiology research group at the Department of Physiology and Pharmacology at Karolinska Institutet is seeking a highly motivated doctoral student to join the group of Professors Anna Krook and Juleen R Zierath to investigate exercise-induced non-coding RNAs in the regulation of skeletal muscle metabolism. The candidate will have the opportunity to join our research group and work on projects focused on the interplay between exercise and gene regulation in orchestrating the metabolic adaptations of skeletal muscle.

The doctoral student project and the duties of the doctoral student

The project will focus on exercise-induced non-coding RNAs in relation to health and skeletal muscle metabolism and performance. A more precise insight of the molecular and cellular events that occur in type 2 diabetes will improve our current disease management and prevention strategies. The aim is to identify training-responsive ncRNAs in skeletal muscle. Whether these non-coding RNAs are linked to health and muscle performance outcomes following physical activity/exercise will be determined. The student is expected to fulfil the course requirements of the doctoral program, participate in regular group meetings, seminars, present at national/international meetings and take part in routine work within the research team.

What do we offer?

A creative and inspiring environment full of expertise and curiosity. Karolinska Institutet is one of the world's leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. As a doctoral student you are offered an individual research project, a well-educated supervisor, a vast range of elective courses and the opportunity to work in a leading research group. Karolinska Institutet collaborates with prominent universities from all around the world, which ensures opportunities for international exchanges. You will be employed on a doctoral studentship which means that you receive a contractual salary. Employees also have access to our modern gym for free and receive reimbursements for medical care.

Eligibility requirements for doctoral education

In order to participate in the selection for a doctoral position, you must meet the following general (A) and specific (B) eligibility requirements at latest by the application deadline.

It is your responsibility to certify eligibility by following the instructions on the web page Entry requirements (eligibility) for doctoral education.

A) General eligibility requirement
You meet the general eligibility requirement for doctoral/third-cycle/PhD education if you:

  1. have been awarded a second-cycle/advanced/master qualification (i.e. master degree) or
  2. have satisfied the requirements for courses comprising at least 240 credits of which at least 60 credits were awarded in the advanced/second-cycle/master level, or
  3. have acquired substantially equivalent knowledge in some other way in Sweden or abroad.*

Follow the instructions on the web page Entry requirements (eligibility) for doctoral education.

*If you claim equivalent knowledge, follow the instructions on the web page Assessing equivalent knowledge for general eligibility for doctoral education.

B) Specific eligibility requirement

You meet the specific eligibility requirement for doctoral/third-cycle/PhD education if you:

- Show proficiency in English equivalent to the course English B/English 6 at Swedish upper secondary school.

Follow the instructions on the web page English language requirements for doctoral education.

Verification of your documents
Karolinska Institutet checks the authenticity of your documents. Karolinska Institutet reserves the right to revoke admission if supporting documents are discovered to be fraudulent. Submission of false documents is a violation of Swedish law and is considered grounds for legal action.

Skills and personal qualities

The candidate will work on the interplay between exercise and changes in gene regulation in orchestrating the metabolic adaptations of skeletal muscle. Work will be performed in cell lines, primary cells and isolated tissues as well as in a whole-body setting using several model systems. Projects cover disease mechanisms as well as protocol and assay development. The applicant must be ambitious and demonstrate an interest in exercise physiology and metabolism. Research experience in cell biology and molecular biology is an advantage, as is knowledge of metabolic assays in vivo and in vitro. Experience in cell culture, immunoblotting, PCR and tissue processing is also valuable. The candidate must be fluent in English and have excellent writing skills. We are looking for a cooperative candidate who thrives working with others. The candidate will join an enthusiastic, collaborative, hardworking and dynamic team.

Terms and conditions

The doctoral student will be employed on a doctoral studentship maximum 4 years full-time.

Application process

Submit your application and supporting documents through the Varbi recruitment system. Use the button in the top right corner and follow the instructions.

Your application should contain the following documents:

- A personal letter and a curriculum vitae (Swedish or English)
- Degree projects and previous publications, if any (Swedish or English)
- Any other documentation showing the desirable skills and personal qualities described above (Swedish or English)
- Documents certifying your general eligibility (see A above)
- Documents certifying your specific eligibility (see B above)


A selection will be made among eligible applicants on the basis of the ability to benefit from doctoral education. The qualifications of the applicants will be evaluated on an overall basis.

Karolinska Institutet uses the following bases of assessment:

- Documented subject knowledge of relevance to the area of research
- Analytical skill
- Other documented knowledge or experience that may be relevant to doctoral studies in the subject.

 All applicants will be informed when the recruitment is completed.

Your career continues here 

Want to make a difference? Join us and contribute to better health for all

Type of employment PhD placement
Contract type Full time
First day of employment Upon agreement
Salary Monthly salary
Reference number 2-4041/2020
Anna Krook, Professor and supervisor,
Rebecka Jakobsson, HR Officer,
Union representative
Henry Wölling, SEKO,
Gunnel Brolin, OFR,
Helin Norberg, SACO,
Published 25.Sep.2020
Last application date 18.Oct.2020 11:59 PM CET

If you apply for this position please say you saw it on Medicinoxy


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