PhD Position in Internal Medicine and Pediatrics
Ghent University Department of Internal Medicine and Pediatrics
Belgium

PhD Student

Last application date
Oct 01, 2020 09:34
Department
GE35 - Department of Internal Medicine and Pediatrics
Employment category
Doctoral fellow
Contract
Limited duration
Degree
Master degree (MA) in Medicine, Bio-engineering, Veterinary Medicine, Biomedical Sciences, Biology, Biochemistry, Biotechnology or Pharmaceutical Sciences
Occupancy rate
100%
Vacancy Type
Research staff

Job description

Non-alcoholic fatty liver disease (NAFLD) is the most common liver disease worldwide, and develops in the context of obesity and metabolic disorders such as type 2 diabetes. The prevalence is also rapidly increasing in children and adolescents. Despite intensive medical research, a satisfactory treatment for NAFLD is not yet available, except for lifestyle interventions.

We are recruiting a motivated PhD student who will perform research into the mechanisms involved in the progression of liver fibrosis in NAFLD.

This builds upon previous work in our lab, and focuses specifically on the role of metabolic factors in the activation of hepatic stellate cells, which contribute to liver fibrosis via production of collagen. This study relies on a combination of mouse models for adult and pediatric NAFLD, in vitro experiments and a translation section via human samples. Techniques used for data analysis include histology, immunohistochemistry, RNA sequencing, qPCR, ELISA, cell isolation and flow cytometry.

We offer a position for 1 year, which can be extended 3 to 4 years in case of positive evaluations. The student will also apply for a FWO/BOF (local) scholarship. He/she will be able to work in a stimulating environment, will be taught the necessary techniques and will be mentored throughout the project. The intended aim is to obtain a PhD in Medical/Biomedical Sciences.

Profile of the candidate

The candidate

  • Has a master degree (MA) in Medicine, Bio-engineering, Veterinary Medicine, Biomedical Sciences, Biology, Biochemistry, Biotechnology or Pharmaceutical Sciences
  •  Is interested in scientific research on liver disease and metabolic disorders
  •  Is motivated to perform animal research and holds or is motivated to obtain a license for laboratory animal science (FELASA C)
  •  Can integrate himself/herself in a multidisciplinary research group
  •  Is communicative and fluent in English

How to apply

Applicants should send their motivation letter, professional resume (CV), overview of study results and, if applicable, contact details of academic referees, to prof. dr. Anja Geerts (anja.geerts@ugent.be) and dr. Sander Lefere (sander.lefere@ugent.be) before October 1 2020.

After an initial screening and selection based on CV and motivation letter, interviews will take place.

Anticipated starting date: November 1 2020.


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