PhD Scholarship in Heart Development, Congenital Heart Disease and Heart Regeneration (del Monte-Nieto Group, ARMI) Monash University, Australian Regenerative Medicine Institute (ARMI) Australia

PhD Scholarship in Heart Development, Congenital Heart Disease and Heart Regeneration (del Monte-Nieto Group, ARMI)

 

Job No.: 590712

 

Employment Type: Full-time

 

Duration: 3 year fixed-term appointment

 

Location: Australian Regenerative Medicine Institute (ARMI), 15 Innovation Walk, Monash University, Clayton

Remuneration: Annual living allowance based on Monash University’s Research Training Program (RTP), stipend of $27,872 per annum (2019 rate - indexed annually)

 

The Opportunity

The del Monte-Nieto group is seeking multiple enthusiastic PhD candidates interested in cardiovascular research and microscopy to study the molecular and cellular processes controlling heart development, the causes leading to congenital heart disease and to find molecular targets to improve the regenerative capacity of the heart.

 

The successful applicant will gain extensive expertise in animal handling, embryo and tissue dissections, paraffin embedding/sectioning, gene/protein expression analysis including bulk RNAseq, single cell RNAseq, ATACseq, in situ hybridization, qPCR, immunofluorescence, western blot; molecular cloning, ChIP, Luciferase assay, 3D imaging by two-photon, light-sheet microscopy, ultrasound and MRI; and 3D image analysis and quantification. 

 

The heart is a complex biological pump in which tissue interactions and biomechanical forces produced by the heartbeat control its development and function. However, the building plans and gene regulatory networks underpinning its formation are incompletely identified and the knowledge from the different heart components is not well integrated, limiting the application of current knowledge to better understand the causation of congenital and adult heart disease, improve the outcomes for cardiac regeneration, tissue engineering or to develop efficient organ-on-a-chip technology for drug screening.

 

My new laboratory at the Australian Regenerative Medicine Institute (ARMI) is looking for multiple PhD, Masters and Honours students to study heart development, congenital heart disease and heart regeneration by applying the ground-breaking notions described in the new model for cardiac trabeculation that we recently published (del Monte-Nieto G et al., 2018, Nature).

 

The topics for the PhD projects include the study of:

  • The cellular behaviours and molecular pathways controlling heart development

  • The leading causes for congenital heart diseases

  • The identification of target molecules to induce heart regeneration

 

Candidate Requirements

The successful applicant must have the following attributes:

  • An excellent academic track record in biological sciences

  • Interest and commitment

  • Experience in developmental biology, regenerative biology and microscopy would be an advantage

 

Australian resident status would be an advantage but the position is not restricted to Australian residents.

 

Applicants will be considered provided they fulfil the criteria for PhD admission at Monash University. Details of eligibility requirements to undertake a PhD at ARMI are available at http://www.armi.org.au/careers-education/higher-degree-research.

 

Candidates will be required to meet Monash entry requirements, which include English-language skills.

 

Successful applicants will be expected to enrol no later than 1 August 2019.

 

How To Apply

Supervisor: Dr Gonzalo del Monte-Nieto

 

Submit your expression of interest to Dr Gonzalo del Monte-Nieto (Gonzalo.delmontenieto@monash.edu) and include the following:

  • A cover letter that includes a brief statement addressing the Candidate Requirements and the reason for your interest in the project

  • A curriculum vitae, including a list of any published works

  • A full statement of academic record, supported by scanned copies of relevant certified documentation

  • Contact details of two academic referees

 

Closing Date

Wednesday 1 May 2019, 11:55 pm AEDT


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