Post Doc in Experimental Diabetes Research (University of Gothenburg Institute of Neuroscience and Physiology)

Postdoctor in Experimental Diabetes Research Diary id:PAR 2020/872 Employment level:Fixed term Location:Institute of Neuroscience and Physiology Apply by:2020-08-31 The Institute of Neuroscience and Physiology, invites applications for a postdoctoral position at the Department of Physiology. We are seeking a talented Post-Doctoral fellow for an ERC-supported project at the international forefront. You will investigate the molecular mechanisms underlying type 2 diabetes with the long-term goal of finding new anti-diabetic treatments. As a Post-Doctoral fellow, you will have the support of Prof. Anders Rosengren as well as an extensive network within the Wallenberg Centre for Molecular and Translational Medicine, which involves world-leading scientists at four Swedish universities, AstraZeneca and SciLifeLab, which will provide you with the guidance and knowledge you need to develop your career. You will get the opportunity to present at international scientific conferences and publish high-profile papers. The position is supported by an ERC Consolidator grant for 2020-2024 so an additional advertisment of the employment can be considered after the inital two years. Subject area Experimental diabetes research. Subject area description Experimental diabetes research with a focus on cell-physiology and gene expression studies. Job assignments The project is truly translational and you will use human pancreatic islets as the starting point to identify the physiological and gene expression changes that contribute to defective insulin secretion in type 2 diabetes. Interesting observations have shown that there are of pools of beta-cells with different phenotype and functional capacity within an islet. Intriguingly, it has recently been demonstrated that the proportion of such pools is altered in type 2 diabetes. By defining the phenotype and proportion of cellular pools in diabetic and non-diabetic conditions in a more precise manner than has previously been possible, the project has the potential to considerably improve our understanding of beta-cell failure and its reversal. It may also lead to the identification of new targets that can be exploited for beta-cell preservation, which is one of the main goals of diabetes research and an urgent clinical need. You will use a range of cell-physiological and cell-biological techniques as well as qPCR and transfection systems. In addition to the physiological studies you will work closely with experts on single-cell RNA sequencing to study the associated gene expression changes. The ability to couple single-cell gene expression with functional data is an exciting area that hasn't been explored to its full potential, making this an opportunity to make a real difference to the future of medical science. The translational profile of our team means that you will also be able to work with clinical researchers to test and validate the disease relevance of your experimental findings as we have previvously done in e.g. Rosengren AH et al., Science 2010, Tang Y et al., Science Translational Medicine 2014 and Axelsson AS et al., Science Translational Medicine 2017. Eligibility To qualify as a postdoctoral researcher the applicant should hold a PhD in a relevant subject. Since postdoctoral constitutes a qualifying appointment for junior researchers, we aim to target those who have a doctoral degree not older than 3 years from the application deadline. Assessment You must have a PhD degree and are expected to have a strong record of scientific productivity with publications as first author in internationally renowned journals. You must also have an extensive experimental background in cell physiology and/or gene expression studies. Previous research in the diabetes area is beneficial but not required. Strong scientific work ethics and your commitment to develop yourself as a scientist will be important evaluation criteria. You are expected to plan, execute and analyze experiments in an independent manner and to actively contribute scientifically to the group. You must have excellent oral and written communication skills in English and be an excellent team player. Great importance will be attached on personal suitability. Employment The employment is temporary (limited) for 24 months, 100% of full-time and is placed at the Institute of Neuroscience and Physiology. Starting date; as soon as possible or as agreed. Appointment procedure In order to apply for a position at the University of Gothenburg, you have to register an account in our online recruitment system. For further information If you have questions regarding the position please contact Professor Anders Rosengren, phone; +46 705316704, e-mail;anders.rosengren@gu.se or Senior Lecturer/Head of Department Lars-Gunnar Pettersson, phone;+4631-786 35 07, e-mail; lars-gunnar.pettersson@gu.se Unions Union representatives at the University of Gothenburg: http://www.gu.se/english/about_the_university/job-opportunities/union-representatives Information for International Applicants Choosing a career in a foreign country is a big step. Thus, to give you a general idea of what we and Gothenburg have to offer in terms of benefits and life in general for you and your family/spouse/partner please visit: https://www.gu.se/english/welcomeservices/staff https://www.movetogothenburg.com/ How to apply In order to apply for a position at the University of Gothenburg, you have to register an account in our online recruitment system. It is the responsibility of the applicant to ensure that the application is complete in accordance with the instructions in the job advertisement, and that it is submitted before the deadline. The selection of candidates is made on the basis of the qualifications registered in the application. Please enclose PhD certificate with the application. Closing date: 20-08-31. The University of Gothenburg promotes equal opportunities, equality and diversity. Salary is determined on an individual basis. Applications will be destroyed or returned (upon request) two years after the decision of employment has become final. Applications from the employed and from those who appeal the decision will not be returned. If you apply for this position please say you saw it on Medicinoxy

Postdoctor in Experimental Diabetes Research

Diary id:PAR 2020/872

Employment level:Fixed term

Location:Institute of Neuroscience and Physiology

Apply by:2020-08-31

The Institute of Neuroscience and Physiology, invites applications for a postdoctoral position at the Department of Physiology.

We are seeking a talented Post-Doctoral fellow for an ERC-supported project at the international forefront. You will investigate the molecular mechanisms underlying type 2 diabetes with the long-term goal of finding new anti-diabetic treatments.

As a Post-Doctoral fellow, you will have the support of Prof. Anders Rosengren as well as an extensive network within the Wallenberg Centre for Molecular and Translational Medicine, which involves world-leading scientists at four Swedish universities, AstraZeneca and SciLifeLab, which will provide you with the guidance and knowledge you need to develop your career. You will get the opportunity to present at international scientific conferences and publish high-profile papers. The position is supported by an ERC Consolidator grant for 2020-2024 so an additional advertisment of the employment can be considered after the inital two years.

Subject area

Experimental diabetes research.

Subject area description

Experimental diabetes research with a focus on cell-physiology and gene expression studies.

Job assignments

The project is truly translational and you will use human pancreatic islets as the starting point to identify the physiological and gene expression changes that contribute to defective insulin secretion in type 2 diabetes. Interesting observations have shown that there are of pools of beta-cells with different phenotype and functional capacity within an islet. Intriguingly, it has recently been demonstrated that the proportion of such pools is altered in type 2 diabetes. By defining the phenotype and proportion of cellular pools in diabetic and non-diabetic conditions in a more precise manner than has previously been possible, the project has the potential to considerably improve our understanding of beta-cell failure and its reversal. It may also lead to the identification of new targets that can be exploited for beta-cell preservation, which is one of the main goals of diabetes research and an urgent clinical need.

You will use a range of cell-physiological and cell-biological techniques as well as qPCR and transfection systems. In addition to the physiological studies you will work closely with experts on single-cell RNA sequencing to study the associated gene expression changes. The ability to couple single-cell gene expression with functional data is an exciting area that hasn't been explored to its full potential, making this an opportunity to make a real difference to the future of medical science.

The translational profile of our team means that you will also be able to work with clinical researchers to test and validate the disease relevance of your experimental findings as we have previvously done in e.g. Rosengren AH et al., Science 2010, Tang Y et al., Science Translational Medicine 2014 and Axelsson AS et al., Science Translational Medicine 2017.

Eligibility

To qualify as a postdoctoral researcher the applicant should hold a PhD in a relevant subject. Since postdoctoral constitutes a qualifying appointment for junior researchers, we aim to target those who have a doctoral degree not older than 3 years from the application deadline.

Assessment

You must have a PhD degree and are expected to have a strong record of scientific productivity with publications as first author in internationally renowned journals.

You must also have an extensive experimental background in cell physiology and/or gene expression studies. Previous research in the diabetes area is beneficial but not required. Strong scientific work ethics and your commitment to develop yourself as a scientist will be important evaluation criteria.

You are expected to plan, execute and analyze experiments in an independent manner and to actively contribute scientifically to the group. You must have excellent oral and written communication skills in English and be an excellent team player. Great importance will be attached on personal suitability.

Employment

The employment is temporary (limited) for 24 months, 100% of full-time and is placed at the Institute of Neuroscience and Physiology. Starting date; as soon as possible or as agreed.

Appointment procedure

In order to apply for a position at the University of Gothenburg, you have to register an account in our online recruitment system.

For further information

If you have questions regarding the position please contact Professor Anders Rosengren, phone; +46 705316704, e-mail;anders.rosengren@gu.se or Senior Lecturer/Head of Department Lars-Gunnar Pettersson, phone;+4631-786 35 07, e-mail; lars-gunnar.pettersson@gu.se

Unions

Union representatives at the University of Gothenburg: http://www.gu.se/english/about_the_university/job-opportunities/union-representatives

Information for International Applicants

Choosing a career in a foreign country is a big step. Thus, to give you a general idea of what we and Gothenburg have to offer in terms of benefits and life in general for you and your family/spouse/partner please visit:

https://www.gu.se/english/welcomeservices/staff
https://www.movetogothenburg.com/

How to apply

In order to apply for a position at the University of Gothenburg, you have to register an account in our online recruitment system. It is the responsibility of the applicant to ensure that the application is complete in accordance with the instructions in the job advertisement, and that it is submitted before the deadline. The selection of candidates is made on the basis of the qualifications registered in the application.

Please enclose PhD certificate with the application.

Closing date: 20-08-31.

The University of Gothenburg promotes equal opportunities, equality and diversity.

Salary is determined on an individual basis.

Applications will be destroyed or returned (upon request) two years after the decision of employment has become final. Applications from the employed and from those who appeal the decision will not be returned.

If you apply for this position please say you saw it on Medicinoxy

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