Postdoc in the Protein Signaling Program
University of Copenhagen Novo Nordisk Foundation Center for Protein Research
Denmark

Postdoc in the Protein Signaling Program, in the Duxin group

We are looking for a highly motivated and dynamic researcher for a two-year position to start in January or February of 2020.

Information about the Center for Protein Research can be found at: https://www.cpr.ku.dk/

Information about the Duxin laboratory can be found at: https://www.cpr.ku.dk/research/proteinsignaling/duxin-group/

Our research

Dr. Duxin’s research aims at understanding the molecular mechanisms that ensure the accurate replication and maintenance of the genome, and how defects in these processes can become the cause of cancer and other diseases. To this end, the lab is using a cell-free extract system derived from the African frogs, Xenopus laevis. These extracts have the remarkable capacity to recapitulate many aspects of genome maintenance including DNA replication and many DNA repair processes. Using this system, the Duxin group recently described how DNA-protein crosslink repair is tightly coupled to DNA replication (Duxin et al. Cell 2014; Larsen et al. Molecular Cell 2019).

By joining the laboratory you will become part of a dynamic and multi-disciplinary research environment present at CPR that comprises state-of-the-art facilities to protein research including Mass Spectrometry, Protein Imaging, and Protein Production platforms.

Your job

The candidate will primarily focus on identifying and characterizing novel repair pathways that participate in the removal of DNA-protein crosslinks. To this end, the candidate will employ proteome and genome wide approaches combined with the power of the Xenopus system. This includes utilizing and developing many different methods of molecular biology, biochemistry and computational analysis. The candidate will have access to all the state-of-the art facilities present at CPR.

Profile

We are looking for a highly motivated and enthusiastic scientist with the following competencies and experience:

Essential experience and skills:

  • You are required to have a Ph.D. degree in science or equivalent.
  • Strong knowledge in molecular biology or biochemistry is required.
  • Publications in internationally recognized journals is required.
  • Good communication skills, both oral and written.
  • Demonstrate in the letter a particular enthusiasm in mechanisms of genome maintenance.

Place of employment

The employment is at the NNF Center for Protein Research (CPR – www.cpr.ku.dk), University of Copenhagen, located in central Copenhagen. The research environment at CPR is vibrant, ambitious, and international, with approx. 30 different nationalities currently represented. The Center comprises modern laboratories and state-of-the-art facilities within protein science. Seminars with high-profile international speakers and regular internal research seminars are organized at the Center. English is the working language at the Center.

Terms of employment

The employment as postdoc is a full time position for two years. Starting date is 1 January 2020 or soon thereafter.

Salary, pension and terms of employment will be in accordance with the agreement between the Danish Ministry of Finance and AC (Danish Confederation of Professional Associations). Currently, the monthly salary starts at 33,600 DKK/ approx. 4,480 Euro (April 2018-level). Depending on qualifications, a supplement may be negotiated. The employer will pay an additional 17.1 % to your pension fund.

Non-Danish and Danish applicants may be eligible for tax reductions, if they hold a PhD degree and have not lived in Denmark the last 10 years.

The position is covered by the “Memorandum on Job Structure for Academic Staff at the Universities” of June 28, 2013.

Questions

For further information please contact Julien Duxin; julien.duxin@cpr.ku.dk ;www.sund.ku.dk

Foreign applicants may find this link useful: www.ism.ku.dk (International Staff Mobility).

Application procedure

Your online application must be submitted in English by clicking ‘Apply now’ below. Furthermore your application must include the following documents/attachments – all in PDF format:

1. Motivated letter of application (max. two pages).

2. CV incl. education, work/research experience, language skills and other skills relevant for the position.

3. A certified/signed copy of a) PhD certificate and b) Master of Science certificate. If the PhD is not completed, a written statement from the supervisor will do.

4. List of publications.

Application deadline: November 30, 2019, 23.59pm CET

We reserve the right not to consider material received after the deadline, and not to consider applications that do not live up to the abovementioned requirements.

The further process

After the expiry of the deadline for applications, the authorized recruitment manager selects applicants for assessment on the advice of the hiring committee. All applicants are then immediately notified whether their application has been passed for assessment by an unbiased assessor. Once the assessment work has been completed each applicant has the opportunity to comment on the part of the assessment that relates to the applicant him/herself.

You can read about the recruitment process at http://employment.ku.dk/faculty/recruitment-process/

The applicant will be assessed according to the Ministerial Order no. 242 of 13 March 2012 on the Appointment of Academic Staff at Universities.

Interviews are expected to be held in December 2019.

University of Copenhagen wish to reflect the diversity of society and welcome applications from all qualified candidates regardless of age, disability, gender, nationality, race, religion or sexual orientation. Appointment will be based on merit alone.

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Part of the International Alliance of Research Universities (IARU), and among Europe’s top-ranking universities, the University of Copenhagen promotes research and teaching of the highest international standard. Rich in tradition and modern in outlook, the University gives students and staff the opportunity to cultivate their talent in an ambitious and informal environment. An effective organisation – with good working conditions and a collaborative work culture – creates the ideal framework for a successful academic career.

Info

Application deadline: 30-11-2019
Employment start: 01-01-2020
Department/Location: Novo Nordisk Foundation Center for Protein Research


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