Postdoctoral Position in Rheumatology
University of Zurich Center of Experimental Rheumatology
Switzerland

Center of Experimental Rheumatology, Department of Rheumatology

Postdoctoral position
100 %

The Center of Experimental Rheumatology Zurich at the Department of Rheumatology, University Hospital Zurich belongs to the world leading institutes in the study of stromal changes in chronic inflammatory joint diseases and analyses epigenetic, transcriptional and functional changes of synovial fibroblasts in patient's samples.

Responsibilities

The current position comprises the analysis of the spatial distribution and function of distinct synovial fibroblast subtypes identified in synovial tissues. We built an extensive genomic, epigenomic, transcriptomic and single cell RNA-seq data set that we want to complement with spatial transcriptomics data. Furthermore, functional co-culture experiments with synovial fibroblasts and other relevant cell types (monocytes/macrophages, endothelial cell, lymphocytes) will be developed in 3D culture systems.

Profile

We are looking for a highly-motivated post-doctoral researcher with strong expertise in molecular-biology methods as well as in bioinformatics analyses.
Specific qualifications include:
  • Experience in cell culture and standard molecular biology techniques (FACS, Western blotting, qPCR, ELISA, etc.)
  • Expertise in the analysis of –omics data sets and programming skills with R
  • Ability to work independently, high problem-solving skills and strong motivation to learn and establish new methods and protocols
  • High interpersonal, intercultural and social competence with cross-disciplinary aptitude
  • Ability to keep a detailed research log and summarize work in research reports, presentations, abstracts and manuscripts
  • Fluent in oral and written English

We offer

  • Work in an internationally known research lab with an interdisciplinary team
  • Personal development opportunity and independent working conditions
  • Supportive and favorable working environment
  • High quality of location, competitive salary and healthy work/life balance

Place of work

Center of Experimental Rheumatology, Wagistrasse 14, 8952 Schlieren

Start of employment

Employment start date to be mutually agreed.

Contact

Prof. Dr. Caroline Ospelt, MD

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