Professor of Medicine (Catholic University of Leuven)

(ref. BAP-2023-658) About team: The laboratory of Prof. Vermeesch translates and implements novel precision technologies to improve patient care. We use liquid biopsies as a biomarker to monitor and provide early detection of genic and non-genic diseases. Wouter Bossuyt is manager of the genomics core facility and develops NGS technology. Responsibilities Project background: Genomic medicine moves healthcare from being reactive to disease to being predictive to disease onset or from cure to prevention. Next-generation sequencing technologies have leveraged novel concepts to diagnose, treat and monitor diseases. Analysis of free-floating cfDNA from blood or other body fluids - called “liquid biopsy” -represents an emerging tool that enables non-invasive monitoring of tissue dynamics in multiple human physiological and pathological conditions, including pregnancy, cancer and other conditions. In the ONCNGS project we are developing innovative approaches for (epi)genome-wide cfDNA analysis that can lead to novel applications to monitor cancer. In this project you will help build novel pipelines and perform clinical validation studies demonstrating the value of the new approaches. The position: A bio-IT/Software engineer position to advance the development of a multi-omics liquid biopsy platform. You will be integrated in a development team and work towards productization and commercialization. We envision this 2 year academic position to evolve into a long term commercial position. You will: • Define testing requirements and acceptance criteria for system integration tracks. • Ensure the data quality of the migrated data for all requirements (functional and technical). • Take responsibility for the creation of the data migration designs and architecture. • You support the development of the test strategy and provide input for the test scenarios; you test the delivered functionalities. • You are in direct contact with the end-users and translate their requirements into functional design. • You monitor the fit between solution and needs and the implementation of the functional design. Profile You ideally have: •Strong computational, programming and/or data analysis skills with an IT, BioIT or engineering background. •Experience with data application platforms and visualization tools such as DASH Plotly or Shiny. •Experience in designing, testing, and deploying data integration. •Experience with data design, architecture, querying, and data modeling. •Understanding of XML/JSON syntaxes •Good Knowledge in several of the following programming languages: Python, R, bash. •Experience with software development tools such as Visual Studio Code. •Ideally worked in cloud-based systems before, preferably GCP. •Project management skills: able to coordinate multiple work streams simultaneously to meet project deadlines. Offer Working with us: We have onsite access to state-of-the-art facilities, including single cell analysis platforms, Flow cytometry, High-Throughput Sequencing, Bioinformatics, Imaging, high-capacity computing and others. You will be embedded in the KULeuven Genomics Core facility (https://www.genomicscore.be), the largest sequencing facility in Belgium, which offers a broad portfolio of NGS techniques for academic labs, companies, and hospitals. Located in Leuven, a small but vibrant and international town by the river Dijle where centuries of history meet cutting-edge science, we are only a stone’s throw away from the cosmopolitan city of Brussels, the heart of Europe. We are part of the University of Leuven, one of the oldest and most prestigious universities of Europe. Founded in 1425, it is Belgium’s largest university, currently featuring among the best universities in the world according to the Times Higher Education and recently ranked as Europe’s most innovative for the third year in a row. Interested? For more information please contact Prof. dr. Joris Vermeesch, mail: joris.vermeesch@kuleuven.be. You can apply for this job no later than November 15, 2023 via the KU Leuven seeks to foster an environment where all talents can flourish, regardless of gender, age, cultural background, nationality or impairments. If you have any questions relating to accessibility or support, please contact us at diversiteit.HR@kuleuven.be. Employment percentage: Voltijds Location: Leuven Apply before: November 15, 2023 Tags: Menselijke erfelijkheid Download: file If you apply for this position please say you saw it on Medicinoxy

(ref. BAP-2023-658)

About team: The laboratory of Prof. Vermeesch translates and implements novel precision technologies to improve patient care. We use liquid biopsies as a biomarker to monitor and provide early detection of genic and non-genic diseases. Wouter Bossuyt is manager of the genomics core facility and develops NGS technology.

Responsibilities

Project background:
Genomic medicine moves healthcare from being reactive to disease to being predictive to disease onset or from cure to prevention. Next-generation sequencing technologies have leveraged novel concepts to diagnose, treat and monitor diseases. Analysis of free-floating cfDNA from blood or other body fluids - called “liquid biopsy” -represents an emerging tool that enables non-invasive monitoring of tissue dynamics in multiple human physiological and pathological conditions, including pregnancy, cancer and other conditions. In the ONCNGS project we are developing innovative approaches for (epi)genome-wide cfDNA analysis that can lead to novel applications to monitor cancer. In this project you will help build novel pipelines and perform clinical validation studies demonstrating the value of the new approaches.

The position:
A bio-IT/Software engineer position to advance the development of a multi-omics liquid biopsy platform. You will be integrated in a development team and work towards productization and commercialization. We envision this 2 year academic position to evolve into a long term commercial position.

You will:

• Define testing requirements and acceptance criteria for system integration tracks.

• Ensure the data quality of the migrated data for all requirements (functional and technical).

• Take responsibility for the creation of the data migration designs and architecture.

• You support the development of the test strategy and provide input for the test scenarios; you test the delivered functionalities.

• You are in direct contact with the end-users and translate their requirements into functional design.

• You monitor the fit between solution and needs and the implementation of the functional design.

Profile

You ideally have:

•Strong computational, programming and/or data analysis skills with an IT, BioIT or engineering background.

•Experience with data application platforms and visualization tools such as DASH Plotly or Shiny.

•Experience in designing, testing, and deploying data integration.

•Experience with data design, architecture, querying, and data modeling.

•Understanding of XML/JSON syntaxes

•Good Knowledge in several of the following programming languages: Python, R, bash.

•Experience with software development tools such as Visual Studio Code.

•Ideally worked in cloud-based systems before, preferably GCP.

•Project management skills: able to coordinate multiple work streams simultaneously to meet project deadlines.

Offer

Working with us:

We have onsite access to state-of-the-art facilities, including single cell analysis platforms, Flow cytometry, High-Throughput Sequencing, Bioinformatics, Imaging, high-capacity computing and others. You will be embedded in the KULeuven Genomics Core facility (https://www.genomicscore.be), the largest sequencing facility in Belgium, which offers a broad portfolio of NGS techniques for academic labs, companies, and hospitals.

Located in Leuven, a small but vibrant and international town by the river Dijle where centuries of history meet cutting-edge science, we are only a stone’s throw away from the cosmopolitan city of Brussels, the heart of Europe.

We are part of the University of Leuven, one of the oldest and most prestigious universities of Europe. Founded in 1425, it is Belgium’s largest university, currently featuring among the best universities in the world according to the Times Higher Education and recently ranked as Europe’s most innovative for the third year in a row.

Interested?

For more information please contact Prof. dr. Joris Vermeesch, mail: joris.vermeesch@kuleuven.be.

You can apply for this job no later than November 15, 2023 via the

KU Leuven seeks to foster an environment where all talents can flourish, regardless of gender, age, cultural background, nationality or impairments. If you have any questions relating to accessibility or support, please contact us at diversiteit.HR@kuleuven.be.

Employment percentage: Voltijds
Location: Leuven
Apply before: November 15, 2023
Tags: Menselijke erfelijkheid
Download: file

If you apply for this position please say you saw it on Medicinoxy

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