Postdoctoral Research Fellow in Biomolecular NMR University of Leeds, School of Molecular & Cellular Biology
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Location: Leeds - Main Campus Faculty/Service: Faculty of Biological Sciences Category: Research Due to funding limitations, an appointment will not be made above £31,656 p.a. Contract Type: Fixed Term (3 years) Project Title: Dynamic mechanisms of FGFR activation in cancer by kinase mutations An MRC-funded 3-year postdoctoral research position is available in Leeds to study dynamic mechanisms of activation of receptor tyrosine kinases by cancer-associated mutations. The project will combine experimental protein biochemistry, protein NMR and biophysics techniques with state-of-the-art computational metadynamics simulations. You will be based in the laboratory of Prof Alex Breeze in the Astbury Centre for Structural Molecular Biology at the University of Leeds, and will also spend time in the group of Prof Michele Vendruscolo (Department of Chemistry, University of Cambridge). Exceptional facilities are available to support the project, including a new, 950 MHz cryoprobe-equipped NMR spectrometer and state-of-the-art computational infrastructure. Applicants should have, or be about to obtain, a PhD in biomolecular NMR, structural biology, biophysics or a related area and have evidence of a good publication track record or potential to achieve one. Successful candidates will be able to demonstrate experience in experimental protein biochemistry, protein NMR and biophysics techniques, though experience in all is not essential and enthusiasm and aptitude to learn is. Start date no later than the 1 December 2016. Informal enquiries may be made to Professor Alex Breeze, tel +44 (0)113 343 0087, email a.l.breeze@leeds.ac.uk Click here for further information about working at the University of Leeds www.leeds.ac.uk/info/20025/university_jobs
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