Research Associate - Blood and Transplant Research Unit in Organ Donation and Transplantation (Fixed Term) University of Cambridge Department of Surgery United Kingdom

Research Associate - Blood and Transplant Research Unit in Organ Donation and Transplantation (Fixed Term)

 

We are seeking a research associate to join our research team, led by Professor Michael Nicholson, in the University of Cambridge Department of Surgery. The post is funded by the National Institute for Health Research (NIHR) Blood and Transplant Research Unit (BTRU) in Organ Donation and Transplantation (http://odt.btru.nihr.ac.uk) and will be based at Addenbrooke's Hospital on the Cambridge Biomedical Campus (http://cambridge-biomedical.com).

 

The BTRU in Organ Donation and Transplantation is one of four BTRUs funded by the NIHR in the UK and is a partnership between the University of Cambridge, Newcastle University and NHS Blood and Transplant (NHSBT). The overarching aim of the BTRU is to develop and evaluate novel approaches and technologies that will increase the availability of suitable donor organs for transplantation, while improving graft survival.

 

The successful candidate will be involved in our translational programmes of research using novel organ perfusion technologies to investigate the cellular and molecular processes involved in kidney damage and repair.

 

We have developed a new technology called normothermic machine perfusion (NMP) which restores function to the kidney before it undergoes transplantation. Using an adapted cardiac bypass system, a red blood cell based solution is circulated through the kidney at near normal pressure and temperature. The kidney is revived and function is restored. The technique has three important roles:

  • reducing injury to the kidney before transplantation
  • allowing an assessment of the quality of the kidney
  • allowing therapies to be given directly to the kidney, avoiding treatment of the donor or recipient.

 

The post-holder will be involved in a range of projects investigating the mechanistic effects of NMP and the delivery of therapies using this technology and will carry out their own research as well as supporting PhD students and researchers within the laboratory and clinical programmes.

 

Candidates should have a PhD or equivalent in a relevant area (e.g. molecular and cellular biology). No prior experience in perfusion technologies is necessary; however, a working knowledge of laboratory techniques, including qPCR, flow cytometry, immunohistochemistry, Western blotting and statistical and data analysis, is essential.

 

Please send informal enquiries by email to Dr Sarah Hosgood (sh744@cam.ac.uk).

 

Fixed-term: The funds for this post are available for 1 years in the first instance.

 

Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment and an enhanced Disclosure and Barring Service check. This appointment also requires a Research Passport application.

 

Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.

 

Closing Date - 7th May 2019

 

Interview Date - Week commencing 27th May 2019

 

Please ensure that you upload your Curriculum Vitae (CV) and a covering letter in the Upload section of the online application. The covering letter should outline how you match the criteria for the post and why you are applying for this role. If you upload any additional documents which have not been requested, we will not be able to consider these as part of your application.

 

Please include details of your referees, including e-mail address and phone number, one of which must be your most recent line manager

 

Please quote reference RE18769 on your application and in any correspondence about this vacancy.

 

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

 

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

 

Further information


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