Research Fellow in Medical Sciences
University of Sussex Brighton and Sussex Medical School
United Kingdom

Research Fellow 

School/department: Brighton and Sussex Medical School

Hours: full time

Contract: fixed term for 36 months

Reference: 4006

Salary: starting at £33,797 to £40,322 per annum     

Placed on: 30 June 2020

Closing date: 12 August 2020.  Applications must be received by midnight of the closing date.

Expected start date: TBC

Job description

Applications are invited for a full-time Research Fellow to work in the laboratory of Dr Lisa Mullen at the Brighton and Sussex Medical School on an MRC-funded project to develop a new therapeutic strategy for treating Osteoarthritis using our recently described engineered TIMP-3 to inhibit aggrecanases. The project will involve in vitro and in vivo characterisation of recombinant TIMP-3 to determine how this protein can be engineered for the greatest therapeutic benefit with a focus on protein biochemistry, cell- and tissue-based assays and analyses of tissue by immunohistochemistry and histology. 

Applicants for this position should possess an Honours B.Sc (or equivalent) in Biochemistry or a related subject and a Ph.D (or equivalent) in Biochemistry, Recombinant Protein Engineering, Joint Disease or a related subject. Experience of murine models of joint disease and a good working knowledge of a range of methods for analysing ex vivo tissue is essential. Previous experience of relevant laboratory work, Home Office Modules 1-4 and good communication skills are essential, as is the ability to work both independently and as part of a team.

The post is based at the Brighton and Sussex Medical School (BSMS) on the University of Sussex campus. At BSMS, we provide a stimulating and supportive environment with our expertise covering a wide range of experimental systems related to Biomedical Research. Further information about our research can be obtained from our website at http://www.bsms.ac.uk/research/

For informal enquires and for more information, please contact Dr Lisa Mullen (l.mullen@bsms.ac.uk).

How to apply

Email your completed application, and personal details and equal opportunities form, to bsmsrecruitment@sussex.ac.uk 

You should attach your application form and all documents to the email (don't use a web-based upload/weblink service) and use the format job reference number / job title / your name in the subject line.

You can also send your application by post to Human Resources Division, Sussex House, University of Sussex, Falmer, Brighton, BN1 9RH.


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