Research Fellow School/department: Brighton and Sussex Medical School Hours: full time Contract: fixed term for 36 months Reference: 4006 Salary: starting at £33,797 to £40,322 per annum Placed on: 30 June 2020 Closing date: 12 August 2020. Applications must be received by midnight of the closing date. Expected start date: TBC Job description Applications are invited for a full-time Research Fellow to work in the laboratory of Dr Lisa Mullen at the Brighton and Sussex Medical School on an MRC-funded project to develop a new therapeutic strategy for treating Osteoarthritis using our recently described engineered TIMP-3 to inhibit aggrecanases. The project will involve in vitro and in vivo characterisation of recombinant TIMP-3 to determine how this protein can be engineered for the greatest therapeutic benefit with a focus on protein biochemistry, cell- and tissue-based assays and analyses of tissue by immunohistochemistry and histology. Applicants for this position should possess an Honours B.Sc (or equivalent) in Biochemistry or a related subject and a Ph.D (or equivalent) in Biochemistry, Recombinant Protein Engineering, Joint Disease or a related subject. Experience of murine models of joint disease and a good working knowledge of a range of methods for analysing ex vivo tissue is essential. Previous experience of relevant laboratory work, Home Office Modules 1-4 and good communication skills are essential, as is the ability to work both independently and as part of a team. The post is based at the Brighton and Sussex Medical School (BSMS) on the University of Sussex campus. At BSMS, we provide a stimulating and supportive environment with our expertise covering a wide range of experimental systems related to Biomedical Research. Further information about our research can be obtained from our website at http://www.bsms.ac.uk/research/ For informal enquires and for more information, please contact Dr Lisa Mullen (l.mullen@bsms.ac.uk). How to apply Email your completed application, and personal details and equal opportunities form, to bsmsrecruitment@sussex.ac.uk You should attach your application form and all documents to the email (don't use a web-based upload/weblink service) and use the format job reference number / job title / your name in the subject line. You can also send your application by post to Human Resources Division, Sussex House, University of Sussex, Falmer, Brighton, BN1 9RH. If you apply for this position please say you saw it on Medicinoxy

Research Fellow

School/department: Brighton and Sussex Medical School

Hours: full time

Contract: fixed term for 36 months

Reference: 4006

Salary: starting at £33,797 to £40,322 per annum

Placed on: 30 June 2020

Closing date: 12 August 2020. Applications must be received by midnight of the closing date.

Expected start date: TBC

Job description

Applications are invited for a full-time Research Fellow to work in the laboratory of Dr Lisa Mullen at the Brighton and Sussex Medical School on an MRC-funded project to develop a new therapeutic strategy for treating Osteoarthritis using our recently described engineered TIMP-3 to inhibit aggrecanases. The project will involve in vitro and in vivo characterisation of recombinant TIMP-3 to determine how this protein can be engineered for the greatest therapeutic benefit with a focus on protein biochemistry, cell- and tissue-based assays and analyses of tissue by immunohistochemistry and histology.

Applicants for this position should possess an Honours B.Sc (or equivalent) in Biochemistry or a related subject and a Ph.D (or equivalent) in Biochemistry, Recombinant Protein Engineering, Joint Disease or a related subject. Experience of murine models of joint disease and a good working knowledge of a range of methods for analysing ex vivo tissue is essential. Previous experience of relevant laboratory work, Home Office Modules 1-4 and good communication skills are essential, as is the ability to work both independently and as part of a team.

The post is based at the Brighton and Sussex Medical School (BSMS) on the University of Sussex campus. At BSMS, we provide a stimulating and supportive environment with our expertise covering a wide range of experimental systems related to Biomedical Research. Further information about our research can be obtained from our website at http://www.bsms.ac.uk/research/

For informal enquires and for more information, please contact Dr Lisa Mullen (l.mullen@bsms.ac.uk).

How to apply

Email your completed application, and personal details and equal opportunities form, to bsmsrecruitment@sussex.ac.uk

You should attach your application form and all documents to the email (don't use a web-based upload/weblink service) and use the format job reference number / job title / your name in the subject line.

You can also send your application by post to Human Resources Division, Sussex House, University of Sussex, Falmer, Brighton, BN1 9RH.

If you apply for this position please say you saw it on Medicinoxy

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